Lakshmi Kuttippurathu

Lakshmi Kuttippurathu, PhD

Boston, MA · lakshmikc@gmail.com · LinkedIn · GitHub

Co-Founder · Encure Biotherapeutics SAB · Bioscope AI ML Advisor · Melior Discovery
About

Computational biology and translational science leader with 15+ years applying data science, genomics, and systems biology to accelerate therapeutic discovery. I build AI-driven platforms that convert complex multi-omics, phenotypic, and clinical datasets into decisions that shape drug programs and investment strategy — from early discovery through preclinical development.

Keynote speaker at Bio-IT World, Festival of Genomics & Biodata, Drug Discovery Strategy Summit, and Single Cell OMICS Conference. Invited speaker and fireside chat guest on AI/ML in Biotech at the Swiss Consulate Boston (2025).

Areas of Expertise
🔬 Translational Science & Precision Medicine
Biomarker discoveryPatient stratificationMechanism-of-action analyticsTarget discovery & validationTranslational data interpretation
🧬 Multi-Omics & Biological Data
GenomicsTranscriptomicsSingle-cell sequencingGWASProteomicsMetabolomicsMulti-modal integration
🤖 AI / ML for Biology
Predictive modelingTarget prioritizationPhenotype stratificationML pipelines for biomedical dataSystems biology modeling
⚙️ Platforms & Infrastructure
Cloud pipelines (AWS)Nextflow / WGS workflowsReproducible workflowsFAIR data environmentsMulti-omics data integration
Current Roles
Co-Founder
2026 – Present

Leading scientific strategy, computational biology, and data-driven decision-making for a cardiometabolic drug discovery platform.

Scientific Advisory Board
Bioscope AI
2026 – Present

Advising on AI-driven precision medicine platform integrating EHR, genomics, and phenotypic data for clinical decision support.

ML Advisor
Melior Discovery
2025 – Present

Leading ML strategy for modeling experimental variability in preclinical disease models to improve reproducibility and statistical power.

Platforms Built
LexGPT AI-driven therapeutic target discovery platform integrating genomic, phenotypic, and clinical datasets
LexMission Cloud-based multi-omics bioinformatics workflow for target prioritization (internal E2E platform)
SMART-3seq Single-cell RNA-seq analysis pipeline (published workflow)
COMPACT Comparative gene expression analysis framework for high-throughput genomic data (published)
CompleteMOTIFs Transcription factor binding motif discovery platform · adopted by 100+ Harvard researchers
Awards & Recognition
🏆 Excellence in Healthcare Award — Health 2.0 Conference (2025)
🏆 Fluxx Award — Scientific Contribution to Data-Driven Healthcare (2025)
🏆 Top Biotech Leader — InsightSuccess Magazine (2025)
🏆 Women Leaders in Biotechnology — Empire Magazine (2025)
🏆 NIH/NIAAA Young Investigator Award — International Symposium for Hepatic Sinusoidal Research
Lakshmi Kuttippurathu, PhD · Boston, MA